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Malic acid, an organic dicarboxylic acid with two stereoisomeric forms, plays an important biochemical role in both the Calvin cycle and the citric acid cycle. It is used as a food additive and preservative, a therapeutic agent, and a dietary supplement.
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Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. It significantly reduces total cell numbers and cell viability/metabolic activity in MTS cells and dose-dependently reduces the number of colonies formed by HCT116 and HT29 cells. This product is for research use only.
Potent inhibitor of malic enzyme (ME1) with an IC50 of 0.15 μM
Reduces total cell numbers and cell viability in MTS cells
Dose-dependently reduces colony formation in HCT116 and HT29 cells
Appears as a white to off-white solid
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Malic acid-d3 is the deuterium labeled Malic acid Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears It plays a role in many sour or tart foods[1][2]
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Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. It is intended for research use only and has been shown to significantly impact cell viability and proliferation in various cell lines.
Potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM
Significantly reduces total cell numbers and cell viability/metabolic activity in MTS cells
Dose-dependently reduces the number of colonies formed by HCT116 and HT29 cells
Suitable for research applications
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective brain-penetrant and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease SRT in Fabry’s and Gaucher’s. purity: 99%
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The racemate of L-malic acid; reduces IFN-γ and TNF-α-induced CCL2 and ICAM expression in HaCaT human keratinocytes at 1 mM; inhibits epidermis and dermis thickening, as well as mast cell and eosinophil dermal infiltration in a mouse model of DNBC-induced atopic dermatitis at 10 mM
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D-(+)-Malic acid, also known as D-Malic acid, is an active enantiomer of Malic acid. It serves as a competitive inhibitor of L-(-)malic acid transport. This product is an analytical standard of D-(+)-Malic acid, specifically intended for research and analytical applications.
Competitive inhibitor of L-(-)malic acid transport
Suitable for research and analytical applications
Enantiomer of Malic acid
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Malic acid disodium hydrate is the disodium salt hydrate form of malic acid intended for laboratory biochemical and buffering applications. It is a white to off-white powder with high water solubility and is supplied in small packs for laboratory use. The reagent is documented with storage and solubility data suited for assay workflows.
Disodium salt hydrate form of malic acid, useful as a buffer and biochemical reagent.
High purity: 98.0% suitable for analytical and assay work.
Water soluble: approximately 175 mg/mL (may require ultrasonic assistance).
Stable at room temperature when stored under nitrogen and away from moisture; extended storage in solvent at -20°C to -80°C.
Supplied in small laboratory pack sizes for convenient handling.
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D-(+)-Malic acid is the analytical standard for D-(+)-Malic acid, intended for research and analytical applications. It is an active enantiomer of Malic acid and a competitive inhibitor of L-(-)-malic acid transport.
The compound is an analytical standard, used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Appearance: solid
Color: white to off-white
Initial source: plants Rosaceae Malus pumila Mill. and microorganisms